New research study supports need for transparency in clinical trials
Likelihood of Null Effects of Large NHLBI Clinical Trials Increased over Time (PLOS One): – “…Beginning in approximately 2000, the likelihood of showing a significant benefit in large National Heart Lung, and Blood Institute (NHLBI) funded studies declined. Among the explanations we evaluated, the requirement of prospective registration in Clinicaltrials.gov is most strongly associated with …