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Massive genetic study shows coronavirus mutating and potentially evolving amid rapid U.S. spread

Washington Post – “The largest U.S. genetic study of the virus, conducted in Houston, shows one viral strain outdistancing all of its competitors, and many potentially important mutations. Scientists in Houston on Wednesday released a study of more than 5,000 genetic sequences of the coronavirus, which reveals the virus’s continual accumulation of mutations, one of which may have made it more contagious. That mutation is associated with a higher viral load among patients upon initial diagnosis, the researchers found. The new report, however, did not find that these mutations have made the virus deadlier or changed clinical outcomes. All viruses accumulate genetic mutations, and most are insignificant, scientists say. The new study, which has not been peer-reviewed, was posted Wednesday on the preprint server MedRxiv. It appears to be the largest single aggregation of genetic sequences of the virus in the United States thus far. A larger batch of sequences was published earlier this month by scientists in the United Kingdom, and, like the Houston study, concluded that a mutation that changes the structure of the “spike protein” on the surface of the virus may be driving the outsized spread of that particular strain…”

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